CONTRIBUTION OF RESIDENT MEMORY CD8+ T CELLS TO PROTECTIVE IMMUNITY AGAINST RESPIRATORY SYNCYTIAL VIRUS AND THEIR IMPACT ON VACCINE DESIGN

Contribution of Resident Memory CD8+ T Cells to Protective Immunity against Respiratory Syncytial Virus and Their Impact on Vaccine Design

Worldwide, human respiratory syncytial virus (RSV) is the most common etiological agent for acute lower respiratory tract infections (ALRI).RSV-ALRI is the major cause of hospital admissions in young children, and it can cause in-hospital deaths in children younger than six months old.Therefore, RSV remains one of the pathogens deemed most importan

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Critical care services in Bagmati province of Nepal: A cross sectional survey [version 4; peer review: 4 approved, 2 approved with reservations]

Background This study aimed to assess the current status of critical care services in 13 districts of Bagmati Province in Nepal, with a focus on access, infrastructure, human resources, and intensive care unit (ICU) services.Methods A cross-sectional survey was conducted among healthcare workers employed in 87 hospitals having medical/surgical ICUs

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Duplication and diversification of the LEAFY HULL STERILE1 and Oryza sativa MADS5 SEPALLATA lineages in graminoid Poales

Abstract Background Gene duplication and the subsequent divergence in function of the resulting paralogs End Table via subfunctionalization and/or neofunctionalization is hypothesized to have played a major role in the evolution of plant form.The LEAFY HULL STERILE1 (LHS1) SEPALLATA (SEP) genes have been linked with the origin and diversification o

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